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How Many Cannabinoids Are There?

The fact that more and more cannabinoids have been discovered in recent years is something that will surprise few people. But exactly how many there are is hard to say. In recent years alone, 21 new types of cannabonoids have been discovered. Different sources speak of many dozens or even more than a hundred different types of cannabinoids. Certainly in commercial plants, the substances are occasionally produced by the plants in such a low amount that it is difficult for scientists to determine exactly how much cannabinoids are produced by a cannabis plant.

History On CBD

In the 1940s, around the Second World War, research into active substances in the cannabis plant was started. The aim of the research was to find out to what extent these substances would have medicinal properties and whether they could be used in the health sector.

In 1940, Roger Adams managed to extract the substance CBD from the Cannabis Sativa L plant. Although he had no idea what kind of substance he had removed from the plant, it later turned out – during various tests on animals in 1946 – that CBD did not lead to the feeling of “getting high”.

Composition of CBD and THC Explained

Adams’ research from 1940 was continued in 1963, when Israeli scientists were able to describe down to the molecule how CBD was structured. In 1964 they managed to get the same for THC. The research team also discovered that the substance affected humans through the endocannabinoid system. From that moment on, the number of investigations into THC and CBD has increased exponentially.

Most Important Cannabonoids Known To Date

Cannabis does not immediately make the most famous cannabinoids that belong to the plant, THC and CBD. Instead, it synthesizes various cannabinoid acids. These cannabinoid acids must be “activated” (decarboxylated), usually by heat, to produce the compounds most consumers are looking for (THC or CBD). But in addition to THCA and CBDA, there are a number of related cannabinoid acids that can be produced by cannabis. These are:

  • CBGA (Cannabigerolic acid)
  • THCA (Tetrahydrocannabinolic acid)
  • CBDA (Cannabidiolic acid)
  • CBCA (Cannabichromenenic acid)
  • CBGVA (Cannabigerovarinic acid)
  • THCVA (Tetrahydrocanabivarinic acid)
  • CBDVA (Cannabidivarinic acid)
  • CBCVA (Cannabichromevarinic acid)

21 New Cannabinoids Discovered

Exactly how many cannabinoids there are is still unknown. The main reason for this is that new substances are still being discovered every year by scientists. A research team from Canada managed to find 21 new cannabinoids in 2018. This brought the total number to no less than 132 fabrics and the end does not seem to be in sight.

Of course, it also helps that the lifelong ban on the cannabis plant is canceled by more and more countries, so that researchers can carry out their investigations in full legality.

Recently it appeared that terpenes (the substances that give the plant its scent) can also have a positive influence on the human body.

Almost No Cannabinoid Gets You High

THC is the only plant-based cannabinoid that you know for sure has obvious intoxicating effects. There is some evidence to suggest that THCV may also have intoxicating effects, although it may depend on the dose. However, like most other vegetable cannabinoids, THCV is usually not present in significant amounts in commercial varieties and cannabis products.

Although most cannabinoids from plants do not get you high themselves, their presence can influence the influence of THC on you. The best example of this comes from CBD. Although it does not get you high yourself, it influences the way THC interacts with the CB1 receptors in your endocannabinoid system and can therefore affect how a cannabis product will affect you.